Product Overview
Pramiracetam [N-[2-[bis(propan-2-yl)amino]ethyl]-2-(2-oxopyrrolidin-1-yl)acetamide] is a fat-soluble derivative of Piracetam. It is distinguished in neuro-analytical research by its significantly higher potency and its specialized mechanism of action, which focuses on the cholinergic system rather than direct glutamate receptor modulation.
In laboratory settings, Pramiracetam is utilized primarily to investigate the enhancement of High-Affinity Choline Uptake (HACU) and its secondary effects on cerebral blood flow and neuronal signaling.
Research Specifications:
- Chemical Formula: C₁₄H₂₇N₃O₂
- Molecular Weight: 269.38 g/mol
- Purity: > 99%+ USP Pharmaceutical Grade
- Form: White to Off-White Crystalline Powder
- Solubility: Highly soluble in lipids and organic solvents; poorly soluble in water.
Primary Research Applications:
- HACU Optimization: Researchers use Pramiracetam to study the kinetics of the Choline Transporter, observing how the compound facilitates the uptake of choline into the presynaptic terminals of the hippocampus.
- EEG Pattern Analysis: It is a key subject in studies focusing on the modulation of cortical EEG activity, particularly in models researching the transition from low-frequency to high-frequency brain wave states.
- Nitric Oxide Synthase (NOS) Activity: Studies often employ Pramiracetam to observe its interaction with the nitric oxide system, which plays a critical role in vasodilation and synaptic plasticity.
Research Notice: This chemical reagent is provided in pure powder form strictly for laboratory research, analysis, and developmental use. It is not for human or animal consumption.