Product Overview
Pharmacodynamics of Piracetam in Experimental Amnesia: Potential Pharmacological Strategies for Treatment of Dementia
The Mechanism: Piracetam's Action Against Pharmacological Amnesia
This is not a general guide—it is a detailed, peer-level analysis of Piracetam's neuropharmacology. This volume is essential for any advanced researcher or serious biohacker who demands quantitative proof and mechanistic depth behind their stack.
Pharmacodynamic of Piracetam in Experimental Amnesia dissects Piracetam's protective effects against five distinct models of chemically-induced memory loss (amnesia) in mice, using the gold-standard water maze test. It goes beyond simple observation to systematically contrast Piracetam's efficacy against various agents like Scopolamine (a cholinergic blocker), Cyclohexamide (a protein synthesis inhibitor), and Sodium Nitrite (a hypoxia inducer).
Uncover the Deep Mechanisms:
- Selective Protection: Analyze the precise data showing that Piracetam (200 mg/Kg dose) effectively prevents anterograde amnesia induced by cholinergic and protein synthesis disruption, yet fails to counteract Diazepam-induced amnesia.
- Targeted Retrieval: Review evidence detailing Piracetam's unique ability to attenuate retrograde amnesia produced by both Sodium Nitrite and the PAF-R antagonist BN52021.
- Molecular Rationale: Gain direct insight into the hypothesized cellular mechanisms of action, including the role of increased intracellular calcium, restoration of cerebral proteins, and the critical improvement in brain cell fluidity—the core theory behind its membrane-modulating effects.
This book provides a rigorous, mechanistic framework for understanding Piracetam's potential as a pharmacological strategy for cognitive restoration and is a critical reference for anyone serious about the science of memory and neuroprotection.
Book Specifications:
- Print Length: 120 Pages
- Language: English
- Publisher: LAP LAMBERT Academic Publishing
- ISBN-10: 9783659242625
- ISBN-13: 978-3659242625
- Dimensions:6" x 0.3" x 9"
- Format: Paperback
