Product Overview
The Alkaloid-Rich Botanical Reference Standard
Cat's Claw (Uncaria tomentosa) is a high-purity botanical extract derived from the inner bark of the Amazonian "Cat's Claw" vine. In analytical research, it is classified as a potent immunomodulator and cytokine antagonist. It is specifically valued for its concentration of oxindole alkaloids, which are the primary subjects for investigating cellular longevity and immune system signaling.
Research Specifications:
- Active Constituents: Minimum 3% Total Oxindole Alkaloids (TOA/POA).
- Key Compounds: Mitraphylline, Isomitraphylline, and Pteropodine.
- Purity: > 99%+ USP Pharmaceutical Grade
- Form: Fine Reddish-Brown Powder.
- Solubility: Soluble in ethanol and hydro-alcoholic solutions; partially soluble in water.
Primary Research Applications:
- DNA Repair Enhancement: Researchers utilize Uncaria tomentosa to study the activity of carboxy alkyl esters (CAE), which are hypothesized to facilitate the repair of single and double-strand DNA breaks in human leucocytes.
- NF-κB Inhibition: It is a key subject in studies focusing on the suppression of Nuclear Factor-kappa B, a primary transcription factor involved in the inflammatory response and cellular stress.
- Amyloid Proteolysis: Investigated for its potential to inhibit the formation of amyloid-beta fibrils and promote the dissolution of existing plaque-like structures in neuro-analytical models.
Research Notice: This botanical reagent is provided in a standardized extract form strictly for laboratory research and development. It is not for human or animal consumption.