Product Overview
Aniracetam (1-anisoyl-2-pyrrolidinone) is a fat-soluble analogue of the prototypical nootropic Piracetam. Due to its lipid solubility, it exhibits a distinct pharmacokinetic profile in laboratory models, allowing for efficient penetration of the blood-brain barrier.
In neuro-analytical research, Aniracetam is primarily utilized to study the positive allosteric modulation of AMPA-type glutamate receptors and its influence on cholinergic and serotonergic signaling.
Research Specifications:
- Chemical Formula: C₁₂H₁₃NO₃
- Molecular Weight: 19.24 g/mol
- Purity: > 99%+ USP Pharmaceutical Grade
- Form: Fine White Crystalline Powder
- Solubility: Poorly soluble in water; highly soluble in lipids, ethanol, and DMSO.
Primary Research Applications:
- AMPA Receptor Modulation: Researchers use Aniracetam to investigate its role as an AMPAkine, specifically observing how it slows the desensitization and deactivation of AMPA receptors to enhance synaptic transmission.
- Anxiolytic Mechanism Studies: It is a key subject in studies exploring the interaction between the cholinergic system and 5HT-2A and D2 receptors, often used to observe behavioral shifts in animal stress models.
- Glutamatergic Plasticity: Studies often employ Aniracetam to observe its effects on Long-Term Potentiation (LTP) in hippocampal slices, providing insights into the molecular basis of memory formation.
Research Notice: This chemical reagent is provided in pure powder form strictly for laboratory research, analysis, and developmental use. It is not for human or animal consumption.
