Product Overview
Adrafinil (2-benzhydrylsulfonylethanehydroxamic acid) is a synthetic compound originally developed in the 1970s. It serves as a prodrug to Modafinil, meaning it undergoes hepatic metabolism to convert into its active metabolite.
In laboratory research, Adrafinil is primarily utilized to investigate the mechanisms of selective alpha-1 adrenergic activity and the modulation of wakefulness without the peripheral stimulation typical of traditional amphetamines.
Research Specifications:
- Chemical Formula: C₁₅H₁₅NO₃S
- Molecular Weight: 289.35 g/mol
- Purity: > 99% USP Pharmaceutical Grade
- Form: Fine Off-White to Light Pinkish Powder
- Solubility: Sparingly soluble in water; soluble in organic solvents like DMSO and Ethanol.
Primary Research Applications:
- Metabolic Conversion Studies: Researchers use Adrafinil to study the enzymatic pathways of the liver, specifically how the compound is metabolized into modafinil and modafinil acid.
- Vigilance & Arousal Signaling: It is a key subject in studies focusing on the hypocretin/orexin system and its role in regulating the sleep-wake cycle in animal models.
- Non-Stimulant Wakefulness: Investigated for its ability to promote alertness while maintaining a low affinity for dopamine transporters, helping researchers differentiate between "wakefulness-promoting" and "stimulant" pathways.
Research Notice: This compound is a potent synthetic reagent provided strictly for laboratory research and development. Due to its metabolic path, it is often utilized in studies involving hepatic enzyme monitoring. Not for human or animal consumption.
